Adjust
administration rate to urgency (give more slowly when perfusing rhythm
present)
Use
caution when administering with other drugs that prolong QT (consider
expert consultation)
Atropine
0.02
mg/kg IV/IO
0.03 mg/kg ET*
Higher
doses may be used with organophosphate poisoning
Repeat
once if needed
Minimum
dose: 0.1 mg
Maximum
single dose:
Child 0.5 mg
Adolescent 1 mg
Calcium
chloride (10%)
20
mg/kg IV/IO (0.2 mL/kg)
Slowly
Adult
dose: 5-10 mL
Epinephrine
0.01
mg/kg (0.1 mL/kg 1:10 000) IV/IO
May
repeat q 3-5 min
0.1
mg/kg (0.1 mL/kg 1:1000) ET*
Maximum
dose: 1 mg IV/IO; 10 mg ET
Glucose
0.5-1
g/kg IV/IO
D10W:
5-10 mL/kg
D25W:
2-4 mL/kg
D50W:
1-2 mL/kg
Lidocaine
Bolus:
1 mg/kg IV/IO
Maximum
dose: 100 mg
Infusion:
20-50 µg/kg per minute
ET*:
2-3 mg
Magnesium
sulfate
25-50
mg/kg IV/IO over 10-20 min; faster in torsades
Maximum
dose: 2g
Naloxone
<5
y or 20 kg: 0.1 mg/kg IV/IO/ET*
5 y or >20 kg: 2 mg IV/IO/ET*
Use
lower doses to reverse respiratory depression associated with therapeutic
opioid use (1-15 µg/kg)
Procainamide
15
mg/kg IV/IO over 30-60
Monitor
ECG and blood pressure
Adult
dose: 20 mg/min IV infusion up to total maximum dose 17 mg/kg
Use
caution when administering with other drugs that prolong QT (consider
expert consultation)
Sodium
bicarbonate
1
mEq/kg per dose IV/IO slowly
After
adequate ventilation
IV indicates
intravenous; IO, intraosseous; and ET, via endotracheal tube.
*Flush with
5 mL of normal saline and follow with 5 ventilations.
Medications
to Maintain Cardiac Output and for Postresuscitation Stabilization
Medication
Dose
Range
Comment
Inamrinone
0.75-1
mg/kg IV/IO over 5 minutes; may repeat x 2; then: 2-20 µg/kg
per minute
Inodilator
Dobutamine
2-20
µg/kg per minute IV/IO
Inotrope;
vasodilator
Dopamine
2-20
µg/kg per minute IV/IO
Inotrope;
chronotrope; renal and splanchnic vasodilator in low doses; pressor
in high doses
Epinephrine
0.1-1
µg/kg per minute IV/IO
Inotrope;
chronotrope; vasodilator in low doses; pressor in higher doses
Milrinone
50-75
µg/kg IV/IO over 10-60 min then 0.5-0.75 µg/kg per minute
Inodilator
Norepinephrine
0.1-2
µg/kg per minute
Inotrope;
vasopressor
Sodium
nitroprusside
1-8
µg/kg per minute
Vasodilator;
prepare only in D5W
IV
indicates intravenous; and IO, intraosseous.
Alternative formula for calculating an infusion:
Infusion rate (mL/h) = [weight (kg) x dose (µg/kg/min) x 60 (min/h)]/concentration
µg/mL).
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